Stability of Clinical Chemistry Analytes in Blood Collection Devices
نویسندگان
چکیده
منابع مشابه
Impact of blood collection devices on clinical chemistry assays.
Blood collection devices interact with blood to alter blood composition, serum, or plasma fractions and in some cases adversely affect laboratory tests. Vascular access devices may release coating substances and exert shear forces that lyse cells. Blood-dissolving tube additives can affect blood constituent stability and analytical systems. Blood tube stoppers, stopper lubricants, tube walls, s...
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Primary investigations of biological fl uids and tissues are routinely conducted to identify applications of diagnostic and therapeutic importance (Subramanian, 1995). In clinical pathology, analyses of plasma or serum samples are essential tools to ascertain the toxicological impact of a test chemical. However, the integrity of the fi ndings not only depends on the analytical instrument and eq...
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Improper design or use of blood collection devices can adversely affect the accuracy of laboratory test results. Vascular access devices, such as catheters and needles, exert shear forces during blood flow, which creates a predisposition to cell lysis. Components from blood collection tubes, such as stoppers, lubricants, surfactants, and separator gels, can leach into specimens and/or adsorb an...
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ژورنال
عنوان ژورنال: Clinical Chemistry
سال: 2000
ISSN: 0009-9147,1530-8561
DOI: 10.1093/clinchem/46.5.737